Enzalutamide
- Catalog NO.:A25302
- CAS No. : 915087-33-1
- Molecular Formula:C21H16F4N4O2S
- Molecular Weight: 464.44
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Product Details
CAS Number | 915087-33-1 | Appearance | White powder |
Catalog Number | A25302 | MDL Number | MFCD14155804 |
Molecular Formula | C21H16F4N4O2S | Molecular Weight | 464.44 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302 | Class | |
Precautionary Statements | P280-P305+P351+P338 | Packing Group |
Description
Enzalutamide, also known as MDV3100, is an orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. Through a mechanism that is reported to be different from other approved AR antagonists, selective androgen receptor modulator MDV3100 inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation and, correspondingly, a reduction in the serum prostate specific antigen (PSA) level. In August 2012, the United States (U.S.) Food and Drug Administration (FDA) approved enzalutamide for the treatment of castration-resistant prostate cancer. |